IgA Polyclonal Antibody
Product Specifications
Background
Disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t (1;14) (q21; q32) that forms a FCRL4-IGHA1 fusion protein., function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system., PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352., similarity:Contains 3 Ig-like (immunoglobulin-like) domains., subunit:Monomeric or polymeric.
Product Name Alternative
IGHA1; Ig alpha-1 chain C region; IGHA2; Ig alpha-2 chain C region
Gene ID
3493/3494
Swiss Prot
P01876/P01877
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
38
Storage Conditions
-20°C/1 year
Protein Weight
38
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
