GROβ rabbit pAb

Function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta (5-73) shows a highly enhanced hematopoietic activity., online information:CXCL2 entry, pharmaceutical:GRO-beta (5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias., PTM:The N-terminal processed form GRO-beta (5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells., similarity:Belongs to the intercrine alpha (chemokine CxC) family.

C-X-C motif chemokine 2 (Growth-regulated protein beta; Gro-beta; Macrophage inflammatory protein 2-alpha; MIP2-alpha) [Cleaved into: GRO-beta (5-73; GRO-beta-T; Hematopoietic synergistic factor; HSF; SB-251353) ]