Gremlin-2 Polyclonal Antibody
Product Specifications
Background
Gremlin 2, DAN family BMP antagonist (GREM2) Homo sapiens This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]
Product Name Alternative
Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; Protein related to DAN and cerberus)
Gene ID
64388
Swiss Prot
Q9H772
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
19
Storage Conditions
-20°C/1 year
Protein Weight
19
Available Sizes
Curated Selection
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