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GDF-8 Polyclonal Antibody

Product Specifications

Background

Myostatin (MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016]

Product Name Alternative

MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin

Gene ID

2660

Swiss Prot

O14793

Cross Reactivity

Human; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

IHC-p; IF (paraffin section) ; ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

-20°C/1 year

Available Sizes

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