GABA A Receptor α4 Polyclonal Antibody
Product Specifications
Background
Gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1) . Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
Product Name Alternative
GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA (A) receptor subunit alpha-4
Gene ID
2557
Swiss Prot
P48169
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section)
Dilution
WB 1:1000-2000, IHC 1:100-200
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
62
Storage Conditions
-20°C/1 year
Protein Weight
62
Available Sizes
Curated Selection
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