FOP Polyclonal Antibody
Product Specifications
Background
FGFR1 oncogene partner (FGFR1OP) Homo sapiens This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t (6;8) (q27; p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
Product Name Alternative
FGFR1OP; FOP; FGFR1 oncogene partner
Gene ID
11116
Swiss Prot
O95684
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF/ICC; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
43
Storage Conditions
-20°C/1 year
Protein Weight
43
Available Sizes
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