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Fhit (phospho Tyr114) Polyclonal Antibody

Product Specifications

Background

Fragile histidine triad (FHIT) Homo sapiens This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

Product Name Alternative

FHIT; Bis (5'-adenosyl) -triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1, P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein

Gene ID

2272

Swiss Prot

P49789

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

IHC-p; IF (paraffin section) ; ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

-20°C/1 year

Available Sizes

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