FETUA rabbit pAb

Function:Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions., polymorphism:There are two common alleles, AHSG*1 and AHSG*2. AHSG*1 has Thr-248/Thr-256; AHSG*2 has Met-248/Ser-256., similarity:Belongs to the fetuin family., similarity:Contains 2 cystatin domains., subunit:Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond., tissue specificity:Synthesized in liver and selectively concentrated in bone matrix. Secrete din plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B]