Epac Polyclonal Antibody

Caution:It is uncertain whether Met-1 or Met-43 is the initiator., domain:The DEP domain is involved in membrane localization independent from regulation by cAMP., function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP., similarity:Contains 1 cyclic nucleotide-binding domain., similarity:Contains 1 DEP domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 Ras-GEF domain., tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.

RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP