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DARPP-32 (phospho Thr75) Polyclonal Antibody

Product Specifications

Background

Protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B) Homo sapiens This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Product Name Alternative

PPP1R1B; DARPP32; Protein phosphatase 1 regulatory subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein

Gene ID

84152

Swiss Prot

Q9UD71

Cross Reactivity

Human; Mouse; Rat; Monkey

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF (paraffin section) ; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

32

Storage Conditions

-20°C/1 year

Protein Weight

32

Available Sizes

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