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DAN Polyclonal Antibody

Product Specifications

Background

Neuroblastoma 1, DAN family BMP antagonist (NBL1) Homo sapiens This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013]

Product Name Alternative

NBL1; DAN; DAND1; Neuroblastoma suppressor of tumorigenicity 1; DAN domain family member 1; Protein N03; Zinc finger protein DAN

Gene ID

4681

Swiss Prot

P41271

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF/ICC; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

19

Storage Conditions

-20°C/1 year

Protein Weight

19

Available Sizes

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