Dab1 (Phospho Tyr220) rabbit pAb

Domain:The PID domain specifically binds to the Asn-Pro-Xaa-Tyr (P) motif found in many tyrosine-phosphorylated proteins., function:Adapter molecule functioning in neural development. May regulate SIAH1 activity., PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity) . Also phosphorylated on Ser-524 independently of reelin signaling., similarity:Contains 1 PID domain., subunit:Associates with the SH2 domains of SRC, FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity) . Interacts with LRP1.