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CYP24A1 Polyclonal Antibody

Product Specifications

Background

Cytochrome P450 family 24 subfamily A member 1 (CYP24A1) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product Name Alternative

CYP24A1; CYP24; 1; 25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial; 24-OHase; Vitamin D (3) 24-hydroxylase; Cytochrome P450 24A1; Cytochrome P450-CC24

Gene ID

1591

Swiss Prot

Q07973

Cross Reactivity

Human; Rat; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF (paraffin section) ; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

38

Storage Conditions

-20°C/1 year

Protein Weight

38

Available Sizes

Frequently Asked Questions

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