C-Myc Polyclonal Antibody
Product Specifications
Background
V-myc avian myelocytomatosis viral oncogene homolog (MYC) Homo sapiens The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Product Name Alternative
MYC; BHLHE39; Myc proto-oncogene protein; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64; YM3252
Gene ID
4609
Swiss Prot
P01106
Cross Reactivity
Human
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB: 1:1000
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
50, (also ~60KD in some samples)
Storage Conditions
-20°C/1 year
Protein Weight
50, (also ~60KD in some samples)
Available Sizes
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