MLN120B (dihydrochloride)
MLN120B dihydrochloride (ML120B dihydrochloride) is a potent, ATP competitive, and orally active inhibitor of IKKβ with an IC50 of 60 nM. MLN120B inhibits multiple myeloma cell growth in vitro and in vivo and also can be used for the research of rheumatoid arthritis[1][2].
Product Specifications
CAS Number
1782573-78-7
Product Name Alternative
ML120B (dihydrochloride)
UNSPSC
12352005
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mln120b-dihydrochloride.html
Purity
99.73
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; adjust pH to 8 with NaOH; heat to 80°C)
Smiles
ClC1=C(C(NC(C2=CC=CN=C2C)=O)=C3C(C4=C(N3)C=NC=C4)=C1)OC.Cl.Cl
Molecular Formula
C19H17Cl3N4O2
Molecular Weight
439.72
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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