CD329 Polyclonal Antibody
Product Specifications
Background
Sialic acid binding Ig like lectin 8 (SIGLEC8) Homo sapiens Sialic acid-binding immunoglobulin (Ig) -like lectins, or SIGLECs (e.g., CD33 (MIM 159590) ), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]) .[supplied by OMIM, May 2010]
Product Name Alternative
SIGLEC8; SAF2; Sialic acid-binding Ig-like lectin 8; Siglec-8; CDw329; Sialoadhesin family member 2; SAF-2; CD329
Gene ID
27181
Swiss Prot
Q9NYZ4
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
50
Storage Conditions
-20°C/1 year
Protein Weight
50
Available Sizes
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