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CD105 Polyclonal Antibody

Product Specifications

Background

Endoglin (ENG) Homo sapiens This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

Product Name Alternative

Endoglin (CD antigen CD105)

Gene ID

2022

Swiss Prot

P17813

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

IHC-p; IF (paraffin section) ; WB

Dilution

IHC-p 1:50-200, WB 1:500-2000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

72

Storage Conditions

-20°C/1 year

Protein Weight

72

Available Sizes

Frequently Asked Questions

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