BinCARD Polyclonal Antibody
Product Specifications
Background
Function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner., PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 CARD domain., subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol., subunit:Associates with BCL10 by CARD-CARD interaction., tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level) . Expressed in thymus and brain.
Product Name Alternative
C9orf89; Bcl10-interacting CARD protein; BinCARD
Gene ID
84270
Swiss Prot
Q96LW7
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year
Available Sizes
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