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BACE Polyclonal Antibody

Product Specifications

Background

Beta-secretase 1 (BACE1) Homo sapiens This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]

Product Name Alternative

Beta-secretase 1 (EC 3.4.23.46) (Aspartyl protease 2) (ASP2) (Asp 2) (Beta-site amyloid precursor protein cleaving enzyme 1) (Beta-site APP cleaving enzyme 1) (Memapsin-2) (Membrane-associated aspartic protease 2)

Gene ID

23621

Swiss Prot

P56817

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

55

Storage Conditions

-20°C/1 year

Protein Weight

55

Available Sizes

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