6CKine Polyclonal Antibody
Product Specifications
Background
C-C motif chemokine ligand 21 (CCL21) Homo sapiens This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19) . [provided by RefSeq, Sep 2014]
Product Name Alternative
C-C motif chemokine 21 (6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21)
Gene ID
6366
Swiss Prot
O00585
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year
Available Sizes
Curated Selection
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