14-3-3σ (Phospho Ser186) rabbit pAb
Product Specifications
Background
Function:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway., function:p53-regulated inhibitor of G2/M progression., similarity:Belongs to the 14-3-3 family., subcellular location:May be secreted by a non-classical secretory pathway., subunit:Homodimer. Interacts with KRT17 (By similarity) . Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN., tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium.
Product Name Alternative
14-3-3 protein sigma (Epithelial cell marker protein 1; Stratifin)
Gene ID
2810
Swiss Prot
P31947
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
130
Storage Conditions
-20°C/1 year
Protein Weight
130
Available Sizes
Curated Selection
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