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SNRI-IN-1

SNRI-IN-1 (Compound 7a) is a dual serotonin and noradrenaline monoamine reuptake inhibitor, P-glycoprotein Efflux Ratio is 20[1].

Product Specifications

CAS Number

[887766-95-2]

UNSPSC

12352005

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/snri-in-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=CC(C(N([C@H]2CCNC2)C3CCOCC3)=O)=C1Cl

Molecular Formula

C16H20Cl2N2O2

Molecular Weight

343.25

References & Citations

[1]Conrad J, et al. Model of P-Glycoprotein Ligand Binding and Validation with Efflux Substrate Matched Pairs. J Med Chem. 2024 Apr 11;67 (7) :5854-5865.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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