CDK4-CCND2, Human (sf9, GST, Flag, His)
CDK4 protein, acting as a Ser/Thr kinase in the cyclin D-CDK4 complex, critically regulates the G (1) /S transition by phosphorylating and inhibiting RB family members. This activity, specifically hypophosphorylation of RB1 during early G (1) phase, releases E2F and promotes transcription of genes that drive G (1) progression. CDK4-CCND2 Protein, Human (sf9, GST, Flag, His) is the recombinant human-derived CDK4-CCND2, expressed by Sf9 insect cells, with N-His, N-GST, N-Flag labeled tag.
Product Specifications
Product Name Alternative
CDK4-CCND2 Protein, Human (sf9, GST, Flag, His), Human, Sf9 insect cells
UNSPSC
12352202
Type
Reference compound
Assay Protocol
https://www.medchemexpress.com/cytokines/cdk4-ccnd2-protein-human-sf9-gst-flag-his.html
Purity
85.00
Molecular Formula
1019&894 (Gene_ID) P11802-1 (M1-E303) &P30279-1 (E2-L289) (Accession)
Molecular Weight
60.3 KDa & 36.0 KDa
Shipping Conditions
Dry ice
Storage Conditions
Stored at -80°C for 1 year
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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