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Trk B (Phospho-Y817) Polyclonal Antibody

Product Specifications

Background

Neurotrophic receptor tyrosine kinase 2 (NTRK2) Homo sapiens This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Product Name Alternative

BDNF/NT-3 growth factors receptor (EC 2.7.10.1; GP145-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Tropomyosin-related kinase B)

Gene ID

4915

Swiss Prot

Q16620

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

IHC-p; IF (paraffin section) ; WB

Dilution

IHC-p 1:50-200, WB 1:500-2000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

145

Storage Conditions

-20°C/1 year

Protein Weight

145

Available Sizes

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