BAM32 Polyclonal Antibody
Product Specifications
Background
Function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR) -signaling downstream of PI3K., induction:Upon B-cell activation., PTM:Phosphorylated on tyrosine residues., similarity:Contains 1 PH domain., similarity:Contains 1 SH2 domain., subcellular location:Membrane-associated after cell stimulation leading to its translocation., subunit:Interacts with PtdIns (3,4,5) P3 and PLCG2. In vitro, interacts with PtdIns (3,4) P2., tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Product Name Alternative
DAPP1; BAM32; HSPC066; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; hDAPP1; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa
Gene ID
27071
Swiss Prot
Q9UN19
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
32
Storage Conditions
-20°C/1 year
Protein Weight
32
Available Sizes
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