PARP-1 Polyclonal Antibody
Product Specifications
Background
Poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Product Name Alternative
Poly [ADP-ribose] polymerase 1 (PARP-1; EC 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD (+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1)
Gene ID
142
Swiss Prot
P09874
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; WB
Dilution
IHC-p 1:50-200, WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
113
Storage Conditions
-20°C/1 year
Protein Weight
113
Available Sizes
Curated Selection
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