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PI 3 Kinase P85α Rabbit mAb

Product Specifications

Background

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

Product Name Alternative

PIK3R1 ; GRB1 ; Phosphatidylinositol 3-kinase regulatory subunit alpha ; PI3-kinase regulatory subunit alpha

Gene ID

5295

Swiss Prot

P27986

Cross Reactivity

Human, Mouse, Rat

Clonality

Monoclonal

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Dilution

IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000; IP 1:50-200Note:For IHC, wesuggest antigen retrieval with TE buffer pH 9.0

Buffer

Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Molecular Weight

84

Storage Conditions

-20°C/1 year

Protein Weight

84

Available Sizes

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