β-Arrestin 1 mouse mAb
Product Specifications
Background
Arrestin beta 1 (ARRB1) Homo sapiens Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Product Name Alternative
ARB 1; ARB 1; ARB1; ARB1; ARR 1; ARR 1; ARR1; ARR1; ARRB 1; ARRB1; ARRB1; ARRB1_HUMAN; Arrestin 2; Arrestin beta 1; Arrestin beta-1; Beta-arrestin-1.
Gene ID
408
Swiss Prot
P49407
Cross Reactivity
Mouse; Rat; Human
Clonality
Monoclonal
Source
Mouse
Applications
WB
Dilution
Wb 1:500
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
50
Storage Conditions
-20°C/1 year
Protein Weight
50
Available Sizes
Curated Selection
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