TRIM5α Monoclonal Antibody
Product Specifications
Background
Tripartite motif containing 5 (TRIM5) Homo sapiens The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
Product Name Alternative
TRIM5; RNF88; Tripartite motif-containing protein 5; RING finger protein 88
Gene ID
85363
Swiss Prot
Q9C035
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
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