Kras4B G12D-IN-1
Kras4B G12D-IN-1 is a Kras4B G12D inhibitor with anticancer effects. Kras4B G12D-IN-1 decreases Kras protein expression in mouse embryonic fibroblasts (MEF) expressing Kras4B G12D (WO2016179558A1, Comp 994566) [1].
Product Specifications
CAS Number
2042365-85-3
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras4b-g12d-in-1.html
Concentration
10mM
Purity
98.01
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C[C@H](CCC1)CNS(C=C)(=O)=O)C2=C(C=CC(Cl)=C2)OC
Molecular Formula
C16H21ClN2O4S
Molecular Weight
372.87
References & Citations
[1]Frank Mccormick, et al. K-ras modulators. WO2016179558A .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Available Sizes
Frequently Asked Questions
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