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RUNX1 Monoclonal Antibody

Product Specifications

Background

Runt related transcription factor 1 (RUNX1) Homo sapiens Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product Name Alternative

RUNX1; AML1; CBFA2; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha

Gene ID

861

Swiss Prot

Q01196

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

WB; IF/ICC; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage Conditions

-20°C/1 year

Available Sizes

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