PRK2 Monoclonal Antibody

Product Specifications

Background

Catalytic activity:ATP + a protein = ADP + a phosphoprotein., domain:The C1 domain does not bind the diacylglycerol (DAG) ., enzyme regulation:Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation., function:Exhibits a preference for highly basic protein substrates., PTM:Activated by limited proteolysis with trypsin., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 C2 domain., similarity:Contains 1 protein kinase domain., similarity:Contains 3 REM (Hr1) repeats.

Product Name Alternative

PKN2; PRK2; PRKCL2; Serine/threonine-protein kinase N2; PKN gamma; Protein kinase C-like 2; Protein-kinase C-related kinase 2

Gene ID

5586

Swiss Prot

Q16513

Cross Reactivity

Human; Mouse; Rat; Monkey

Clonality

Monoclonal

Source

Mouse

Applications

WB; IHC-p; IF (paraffin section) ; FCM; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage Conditions

-20°C/1 year