PCNA Monoclonal Antibody (12D10), AbFluor™ 647 Conjugated
Product Specifications
Background
Proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Product Name Alternative
PCNA
Gene ID
5111
Swiss Prot
P12004
Cross Reactivity
Human; Rat; Mouse
Clonality
Monoclonal
Source
Mouse
Applications
WB; IF/ICC; IHC-p
Dilution
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 1:200, IF 1:200.
Buffer
Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
Available Sizes
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