Myd88 Mouse mAb (2H12)
Product Specifications
Background
Myeloid differentiation primary response 88 (MYD88) Homo sapiens This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Product Name Alternative
Myeloid differentiation primary response protein MyD88
Gene ID
4615
Swiss Prot
Q99836
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
IHC
Dilution
IHC 1:50-200
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.52% sodium azide.
Molecular Weight
33
Storage Conditions
-20°C/1 year
Protein Weight
33
Available Sizes
Curated Selection
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