Kif 7 Monoclonal Antibody (3F8)
Product Specifications
Background
Kinesin family member 7 (KIF7) Homo sapiens This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]
Product Name Alternative
Kinesin-like protein KIF7
Gene ID
374654
Swiss Prot
Q2M1P5
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
IHC-P; IF/ICC
Dilution
WB 500-2000 1:200 IF 1:50-200
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
Curated Selection
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