Kif 7 Monoclonal Antibody (3F8)

Product Specifications

Background

Kinesin family member 7 (KIF7) Homo sapiens This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011]

Product Name Alternative

Kinesin-like protein KIF7

Gene ID

374654

Swiss Prot

Q2M1P5

Cross Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Source

Mouse

Applications

IHC-P; IF/ICC

Dilution

WB 500-2000 1:200 IF 1:50-200

Buffer

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Conditions

-20°C/1 year