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Keratin8/18 mouse mAb

Product Specifications

Background

Keratin 8 (KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Product Name Alternative

Card2; Cardiac autoantigen 2 120kD; CK 8; CK-8; ck8; Cyk 8; cyk8; CYKER; Cytokeratin 8; Cytokeratin endo A; Cytokeratin-8; Cytokeratin8; DreK8; EndoA; k0; k2c8; K2C8_HUMAN; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; Keratin8; KO; Krt 2.8; Krt8; krt8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8./Cell proliferation inducing gene 46 protein; Cell proliferation inducing protein 46; Cell proliferation-inducing gene 46 protein; CK 18; CK-18; CK18; CYK 18; CYK18; Cytokeratin 18; Cytokeratin endo B; Cytokeratin-18; K 18; K18; K1C18_HUMAN; Keratin 18; Keratin D; keratin, type I cytoskeletal 18; Keratin-18; KRT18.

Gene ID

3856/3875

Swiss Prot

P05787/P05783

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

WB; ICC

Dilution

WB 1:500-2000, ICC 1:50-200

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

55/48

Storage Conditions

-20°C/1 year

Protein Weight

55/48

Available Sizes

Frequently Asked Questions

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