JNK1 mouse mAb

Mitogen-activated protein kinase 8 (MAPK8) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spl

AI849689 ; c Jun N terminal kinase 1 ; C-JUN kinase 1 ; c-Jun N-terminal kinase 1 ; EC 2.7.11.24 ; JAK 1A ; JAK1A ; JNK 1 ; JNK 46 ; JNK ; JNK-46 ; JNK1A2 ; JNK21B1/2 ; MAP kinase 8 ; MAPK 8 ; MAPK8 ; Mitogen activated protein kinase 8 ; Mitogen-activated protein kinase 8 ; MK08_HUMAN ; p54 gamma ; PRKM 8 ; PRKM8 ; Protein kinase JNK1 ; Protein kinase, mitogen-activated, 8 ; SAPK 1 ; SAPK gamma ; SAPK1 ; Stress activated protein kinase JNK1 ; Stress-activated protein kinase 1 ; Stress-activated protein kinase JNK1 ; Tyrosine protein kinase JAK1 .