IRAK-4 Monoclonal Antibody
Product Specifications
Background
Interleukin 1 receptor associated kinase 4 (IRAK4) Homo sapiens This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene ID
51135
Swiss Prot
Q8TDF7
Cross Reactivity
Human; Mouse; Monkey
Clonality
Monoclonal
Source
Mouse
Applications
WB; IHC-p; IF (paraffin section) ; FCM; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
Curated Selection
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