IGF-IR Monoclonal Antibody
Product Specifications
Background
Insulin like growth factor 1 receptor (IGF1R) Homo sapiens This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Product Name Alternative
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221
Gene ID
3480
Swiss Prot
P08069
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
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