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HDAC4 Monoclonal Antibody

Product Specifications

Background

Histone deacetylase 4 (HDAC4) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]

Product Name Alternative

HDAC4; KIAA0288; Histone deacetylase 4; HD4

Gene ID

9759

Swiss Prot

P56524

Cross Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Source

Mouse

Applications

WB

Dilution

Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Conditions

-20°C/1 year

Available Sizes

Frequently Asked Questions

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