HDAC3 Monoclonal Antibody
Product Specifications
Background
Histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
Product Name Alternative
HDAC3; Histone deacetylase 3; HD3; RPD3-2; SMAP45
Gene ID
8841
Swiss Prot
O15379
Cross Reactivity
Human; Mouse; Rat; Dog; Pig; Rabbit
Clonality
Monoclonal
Source
Mouse
Applications
WB
Dilution
Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
Buffer
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
