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GADD45α mouse mAb

Product Specifications

Background

Growth arrest and DNA damage inducible alpha (GADD45A) Homo sapiens This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]

Product Name Alternative

DDIT 1; DDIT-1; DDIT1; DNA damage inducible transcript 1; DNA damage-inducible transcript 1 protein; GA45A_HUMAN; GADD45; GADD45A; Growth arrest and DNA damage inducible 45 alpha; Growth arrest and DNA damage inducible alpha; Growth arrest and DNA damage-inducible protein GADD45 alpha.

Gene ID

1647

Swiss Prot

P24522

Cross Reactivity

Transfected

Clonality

Monoclonal

Source

Mouse

Applications

WB

Dilution

Wb dilution 1:1000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

22

Storage Conditions

-20°C/1 year

Protein Weight

22

Available Sizes

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