COX2 Monoclonal Antibody (3D4)
Product Specifications
Background
Prostaglandin-endoperoxide synthase 2 (PTGS2) Homo sapiens Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Product Name Alternative
PTGS2; COX2; Prostaglandin G/H synthase 2; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2
Gene ID
5743
Swiss Prot
P35354
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
IHC-p; IF (paraffin section)
Dilution
IHC: 1:200
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
70
Storage Conditions
-20°C/1 year
Protein Weight
70
Available Sizes
Curated Selection
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