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Cofilin Mouse mAb (Mix-mA)

Product Specifications

Background

Cofilin 1 (CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Product Name Alternative

Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)

Gene ID

1072

Swiss Prot

P23528

Cross Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Source

Mouse

Applications

IHC-p; WB

Dilution

IHC-p1:50-200 , WB 1:1000-2000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.71% sodium azide.

Molecular Weight

19

Storage Conditions

-20°C/1 year

Protein Weight

19

Available Sizes

Frequently Asked Questions

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