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CD8 Monoclonal Antibody

Product Specifications

Background

CD8a molecule (CD8A) Homo sapiens The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Product Name Alternative

CD8A; MAL; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD antigen CD8a

Gene ID

925

Swiss Prot

P01732

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

FCM; ELISA

Dilution

Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Purified antibody in PBS containing 0.03% sodium azide.

Storage Conditions

-20°C/1 year

Available Sizes

Frequently Asked Questions

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