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CD247 Monoclonal Antibody

Product Specifications

Background

CD247 molecule (CD247) Homo sapiens The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product Name Alternative

CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247

Gene ID

919

Swiss Prot

P20963

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

WB; IHC-p; IF/ICC; FCM; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Buffer

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage Conditions

-20°C/1 year

Available Sizes

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