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CD117 (C-kit) mouse mAb (PT0273)

Product Specifications

Background

KIT proto-oncogene receptor tyrosine kinase (KIT) Homo sapiens This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product Name Alternative

Mast/stem cell growth factor receptor Kit (SCFR; EC 2.7.10.1; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117)

Gene ID

3815

Swiss Prot

P10721

Cross Reactivity

Human

Clonality

Monoclonal

Source

Mouse

Applications

IHC-p; IF (paraffin section) ; WB

Dilution

IHC-p 1:100-300, WB 1:500-2000

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

-20°C/1 year

Available Sizes

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