BNP Monoclonal Antibody
Product Specifications
Background
Natriuretic peptide B (NPPB) Homo sapiens This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014]
Product Name Alternative
NPPB; Natriuretic peptides B; Gamma-brain natriuretic peptide
Gene ID
4879
Swiss Prot
P16860
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
Curated Selection
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