B23 Monoclonal Antibody
Product Specifications
Background
Nucleophosmin (NPM1) Homo sapiens This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009]
Product Name Alternative
NPM1; NPM; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin
Gene ID
4869
Swiss Prot
P06748
Cross Reactivity
Human; Mouse; Rat; Bovine; Pig; Rabbit
Clonality
Monoclonal
Source
Mouse
Applications
WB; IF/ICC
Dilution
Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.
Buffer
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Storage Conditions
-20°C/1 year
Available Sizes
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